Amorphous solid form of compounds containing S—N-valeryl-N-{[2′-(1H-tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine and (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester moieties and sodium cations

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United States of America Patent

PATENT NO 11096918
SERIAL NO

16579581

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Abstract

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An amorphous solid form of a compound comprising the angiotensin receptor antagonist (ARB) valsartan, the neutral endopeptidase inhibitor (NEPi) (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methylpentanoic acid ethyl ester and sodium cations is provided. This compound is useful for the treatment of hypertension and/or heart failure.

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Patent Owner(s)

  • NOVARTIS PHARMACEUTICALS CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blacklock, Thomas J East Hanover, US 24 179
Feng, Lili Pine Brook, US 31 104
Girgis, Michael J Montville, US 21 77
Godtfredsen, Sven Erik Chatham, US 17 69
Hu, Bin Green Brook, US 275 1156
Karpinski, Piotr Henryk Lincoln Park, US 10 34
Liu, Yugang Bridgewater, US 44 127
Prashad, Mahavir Montville, US 44 236
Sutton, Paul Allen Getsville, US 36 203

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