Molecular diagnostic test for cancer

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11091809
APP PUB NO 20160002732A1
SERIAL NO

14649421

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Abstract

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Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test identifies cancer subtypes that have an up-regulation or a down-regulation in biomarker expression related to angiogenesis and vascular development. The present invention can be used to determine whether patients with cancer are clinically responsive or non-responsive to a therapeutic regimen prior to administration of any anti-angiogenic agent. This test may be used in different cancer types and with different drugs that directly or indirectly affect angiogenesis or angiogenesis signalling. In addition, the present invention may be used as a prognostic indicator for certain cancer types. In particular, the present invention is directed to the use of certain combinations of predictive markers, wherein the expression of the predictive markers correlates with responsiveness or non-responsiveness to a therapeutic regimen.

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Patent Owner(s)

Patent OwnerAddress
ALMAC DIAGNOSTIC SERVICES LIMITEDCRAIGAVON BT63 5QD

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bylesjo, Max Glasglow, GB 8 142
Davison, Timothy Hillsborough, GB 31 588
Deharo, Steve Hillsborough, GB 11 101
Gourley, Charlie Dumfermline, GB 5 68
Harkin, Denis Paul Dromore, GB 13 111
Hill, Laura A Lisburn, GB 9 89
Keating, Katherine E Magherafelt, GB 9 104
Kennedy, Richard Belfast, GB 29 312
McCavigan, Andrena Lurgan, GB 7 74
Michie, Caroline Nr Kirkcaldy, GB 2 54
O'Brien, Eamonn J Hillsborough, GB 2 54
O'Donnell, Jude Galbally, GB 9 88
Patterson, Fionnuala Greenisland, GB 9 101
Proutski, Vitali Oxford, GB 8 142
Trinder, Claire Stratford-upon-Avon, GB 3 107
Winter, Andreas Gersthofen, DE 220 6188

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