Method for preparing urate transporter 1 inhibitor

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United States of America Patent

PATENT NO 11091448
APP PUB NO 20190233381A1
SERIAL NO

16312164

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Abstract

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Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.

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Patent Owner(s)

Patent OwnerAddress
TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO LTDTIANJIN 300193

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Huihui Tianjin, CN 11 55
Li, Yuquan Tianjin, CN 7 5
Liu, Changying Tianjin, CN 3 4
Liu, Wei Tianjin, CN 1976 15390
Liu, Yuqiang Tianjin, CN 9 8
Tang, Lida Tianjin, CN 15 45
Wu, Jingwei Tianjin, CN 16 127
Xie, Yafei Tianjin, CN 7 5
Xu, Weiren Tianjin, CN 12 42
Zhang, Haizhi Tianjin, CN 4 4
Zhao, Guilong Tianjin, CN 7 12
Zou, Meixiang Tianjin, CN 8 22

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