1,4,7,10-tetrazacyclododecane based agents to target bacteria and its use

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11072590
APP PUB NO 20170240582A1
SERIAL NO

15503783

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to new compounds comprising a siderophore moiety as well as a core structure able to chelate a metal ion. Optionally, the compounds may have additionally a moiety with a functional element including a marker molecule, a bioactive agent, an activity based probe suitable to monitor the aberrant expression or activity of proteins involved in the initiation and progression of bacterial infection, or a compound useful for bacterial inhibition. In a further aspect, the present invention provides a pharmaceutical composition containing said compound, for example, said pharmaceutical composition is an antibiotic. Additionally, the present invention relates to the use of said compounds in diagnostic methods, in particular, imaging methods including SPEC, PET or MRI. In an embodiment of the present invention, the compound is part of a theranostic composition having both, therapeutic as well as diagnostic activities.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBHINHOFFENSTRASSE 7 BRAUNSCHWEIG D-38124

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Broenstrup, Mark Braunschweig, DE 15 40
Ferreira, Kevin Braunschweig, DE 3 0
Fetz, Verena Braunschweig, DE 2 0
Hu, Haiyu Wolfenbuettel, DE 1 0
Rais, Bushra Lucknow, IN 1 0
Sergeev, Galina Wolfsburg, DE 1 0

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Jan 27, 2025
7.5 Year Payment $3600.00 $1800.00 $900.00 Jan 27, 2029
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jan 27, 2033
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00