Drug-eluting self-retaining sutures and methods relating thereto

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United States of America Patent

PATENT NO 11007296
APP PUB NO 20130317545A1
SERIAL NO

13883066

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Abstract

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A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug release kinetics may be modified uniformly or region by region. The self-retaining suture may for example be used for reattaching severed nerves and release nerve growth factor or other regeneration accelerating agents into the region of the nerve injury.

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Patent Owner(s)

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CILAG GMBH INTERNATIONALGUBELSTRASSE 34 6300 ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avelar, Rui Goleta, US 35 3619
Crow, Brent B Grand Prairie, US 7 451
D'Agostino, William L Hamden, US 26 7914
Drubetsky, Lev Coquitlam, CA 24 1861
Griffin, Nickolas B Allen, US 4 28
Gross, Jeffrey M Carlsbad, US 82 3860
Naimagon, Alexander Richmond, CA 17 1599
Nelson, Kevin Don Richardson, US 1 26

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