Microbubble complexes and methods of use

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United States of America Patent

PATENT NO 11007212
APP PUB NO 20190060347A1
SERIAL NO

16016963

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Abstract

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The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.

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Patent Owner(s)

Patent OwnerAddress
GENERAL ELECTRIC COMPANY1 RIVER ROAD SCHENECTADY NY 12345

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burczak, John Donald Voorheesville, US 4 13
Lim, Hae Won Niskayuna, US 7 63
Lowery, Lisa Anne Niskayuna, US 6 17
Mohan, Praveena Clifton Park, US 3 8
Rothman, James Edward Niskayuna, US 7 92
Sood, Anup Clifton Park, US 81 3535

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