TFPI inhibitors and methods of use

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United States of America Patent

PATENT NO 11001613
APP PUB NO 20180072784A1
SERIAL NO

15681074

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, and/or treat a blood coagulation disorder in a subject.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSASKA-SHI OSAKA 541-0045

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dockal, Michael Vienna, AT 47 164
Ehrlich, Hartmut Vienna, AT 46 206
Polakowski, Thomas Berlin, DE 19 110
Reimer, Ulf Berlin, DE 17 62
Reineke, Ulrich Berlin, DE 34 219
Scheiflinger, Friedrich Vienna, AT 107 597
Schneider, Eberhard Denkte, DE 41 327

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