Pulmonary delivery of progestogen

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10993879
APP PUB NO 20160045396A1
SERIAL NO

14860578

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Abstract

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The present invention relates to a pharmaceutical formulation powder that contains 17α-hydroxyprogesterone caproate (17-OHPC) powder and the method of producing the formulation produces particles that are suitable as an inhalant. The formulations, methods and kits of powdered 17-OHPC as taught herein may be used to reduce cytokine interleukin-17 (IL-17 or IL-17A) levels in both broncheoalveolar lavage fluid (BALF) and blood/serum and involve the inhibition of p38 mitogen activating protein kinase (MAPK) activity. The 17-OHPC powder formulation may be used in a method to treat IL-17 cytokine and/or p38 MAPK mediated auto-immune and auto-inflammatory diseases. Such diseases may include glucocorticoid (GC) insensitive related diseases or conditions. In alternate embodiment, the formulation may include the combined use of budesonide (BUD) and/or fluticasone with 17-OPHC.

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Patent Owner(s)

Patent OwnerAddress
SHENZHEN EVERGREEN THERAPEUTICS CO LTD1504 BLOCK A BUILDING 1 GUANGMING CLOUD PARK NO 98 ZHENYUAN ROAD ZHENMEI COMMUNITY XINHU STREET GUANGMING DISTRICT SHENZHEN GUANGDONG 518107 518107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Du, Tao Tom North Potomac, US 11 81
Lee, Chang Bethesda, US 34 2467

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