Bispecific EGFR/IGFIR binding molecules
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United States of America Patent
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Mar 23, 2021
Grant Date -
May 23, 2019
app pub date -
Nov 30, 2018
filing date -
Nov 24, 2008
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Abstract
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on the tenth fibronectin type III domain.
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