Synthesis and application of chiral substituted polyvinylpyrrolidinones
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United States of America Patent
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Feb 2, 2021
Grant Date -
Oct 1, 2020
app pub date -
Mar 28, 2017
filing date -
Mar 28, 2016
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Abstract
Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.
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