Hybrid oligonucleotides and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10758558
APP PUB NO 20180028557A1
SERIAL NO

15550108

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Abstract

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Provided herein are hybrid oligonucleotides comprising a region that promotes cleavage of a nucleic acid and a region that protects a nucleic acid from exonuclease activity. Such hybrid oligonucleotides are useful for modulating the expression of genes. Related compositions and methods are also provided. In some embodiments, methods are provided for treating a disease, such as by administering a hybrid oligonucleotide.

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Patent Owner(s)

Patent OwnerAddress
TRANSLATE BIO MA INC29 HARTWELL AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ozsolak, Fatih Boston, US 22 199

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