Nucleic acid purification
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United States of America Patent
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Jul 21, 2020
Grant Date -
Nov 3, 2016
app pub date -
Dec 7, 2015
filing date -
Jul 18, 2012
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Abstract
Methods and composition for nucleic acid isolation are provided. In one embodiment, a method is provided for nucleic acid purification from biological samples, such as whole blood samples, extracted with phenol-based denaturing solvents, which does not require phase separation or nucleic acid precipitation. Methods according to the invention may also be used for of small RNAs (e.g., siRNAs or miRNAs) purification and are amenable to automation.
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