Steroid analogues for neuroprotection

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United States of America Patent

PATENT NO 10716795
APP PUB NO 20180221390A1
SERIAL NO

15945678

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Abstract

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Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.

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Patent Owner(s)

Patent OwnerAddress
EMORY UNIVERSITYATLANTA GA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guthrie, David B Avondale Estates, US 14 86
Liotta, Dennis C Atlanta, US 145 2450
Lockwood, Mark A Johns Creek, US 12 74
MacNevin, Christopher Durham, US 3 14
Natchus, Michael G Alpharetta, US 33 110
Sayeed, Iqbal Atlanta, US 18 146
Stein, Donald G Atlanta, US 24 382

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