Methods for purifying antibodies

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United States of America Patent

PATENT NO 10676503
APP PUB NO 20160024146A1
SERIAL NO

14775868

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Abstract

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A method for purifying a protein comprising an antibody, antibody fragment, or immunoglobulin single variable domain, from a solution containing at least one contaminant by superantigen chromatography comprising: a) adsorbing the protein to the superantigen immobilized on a solid support; b) removing the at least one contaminant by contacting the immobilized superantigen containing the adsorbed protein with a first wash buffer comprising an aliphatic carboxylate; and c) eluting the protein from the superantigen immobilized on the solid support.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLLNE INTELLECTUAL PROPERTY (NO 2) LIMITED980 GREAT WEST ROAD BRENTFORD MIDDLESEX TW8 9GS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goklen, Kent E King of Prussia, US 9 36
Suda, Eric J Holly Springs, US 4 33
Ubiera, Antonio Raul King of Prussia, US 4 30

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