Biomarkers and methods to predict response to inhibitors and uses thereof

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United States of America Patent

PATENT NO 10662477
APP PUB NO 20150240315A1
SERIAL NO

14432587

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Abstract

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Disclosed herein are markers associated with sensitivity to treatment with therapeutic agents. Methods to identify markers for predicting outcome to treatment with a therapeutic agent are disclosed as well as methods to predict outcome of treatment using markers. Compositions and methods are provided to predict response to NAE inhibition or EGFR inhibition treatment.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA 5410045 ?5410045

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blakemore, Stephen J Littleton, US 12 22
Li, Bin Belmont, US 1200 10531
Shin, Hyunjin Brookline, US 11 58
Trepicchio, William L Andover, US 14 185

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