Cell engaging binding molecules
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United States of America Patent
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May 19, 2020
Grant Date -
Oct 10, 2019
app pub date -
Apr 1, 2019
filing date -
Apr 10, 2018
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Abstract
The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present disclosure generally related to a binding molecule comprising antibody variable light (VL) regions, variable heavy (VH) regions, constant heavy 1 (CH1) regions, and light chain constant (CL) regions that are configured to form two antigen binding Fab regions and an antigen binding Fv region so that the binding molecule binds to two different antigens.
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