Solid phase TGase-mediated conjugation of antibodies
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United States of America Patent
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Issued Date -
Jan 28, 2016
app pub date -
Mar 14, 2014
filing date -
Mar 15, 2013
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Abstract
Some embodiments described herein relate to solid-support based processes for the functionalization of immunoglobulins through the use of transglutaminase. Also provided are solid support compositions with bound antibody. The methods can be used, for example, in manufacturing processes or in drug screening.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07F:ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CO....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C07D:HETEROCYCLIC COMPOUNDS
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- C07C:ACYCLIC OR CARBOCYCLIC COMPOUNDS
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- C07K:PEPTIDES
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