Methods and systems for the detection of analytes
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United States of America
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Mar 24, 2020
Grant Date -
May 3, 2018
app pub date -
Apr 8, 2016
filing date -
Apr 8, 2016
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Abstract
Provided herein are methods and devices for the detection of analytes. The methods employ particles formed from a first metal conjugated to analytes. The analyte conjugated to the particle formed from the first metal can be accumulated at a working electrode. The first metal can be galvanically exchanged with ions of a second metal to form a layer of the first metal at the working electrode. The first metal can then be electrochemically detected and/or quantified. Using this method, analytes can be detected at low concentrations a few femtomolar via anodic stripping voltammetry, with no washing steps or electrode modifications.
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