Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
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United States of America
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Mar 24, 2020
Grant Date -
Oct 11, 2018
app pub date -
Nov 13, 2017
filing date -
Nov 13, 2017
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Abstract
Novel antibodies and antigen binding fragments that specifically bind to KAAG1 and which may be used in the treatment, detection and diagnosis of cancer comprising KAAG1-expressing cells are disclosed herein. Cells expressing the antibodies and antigen binding fragments as well as methods of detecting and treating cancer using the antibodies and fragments are also disclosed. Cancer indications which may benefit from such treatment or detection include ovarian cancer, renal cancer, lung cancer, colorectal cancer, breast cancer, brain cancer, and prostate cancer, as well as melanomas.
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