Method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains having controlled grain size distribution, and HPMCAS powder

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United States of America

PATENT NO 10562983
APP PUB NO 20160311932A1
SERIAL NO

15104561

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Abstract

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Disclosed are a method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains and HPMCAS grains. The disclosed method for preparing HPMCAS grains comprises: a step of esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst so as to obtain a reaction solution containing HPMCAS (esterification step); and a step of continuously or intermittently putting the reaction solution into water so as to form grains (granulating step).

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Patent Owner(s)

Patent OwnerAddress
LOTTE FINE CHEMICAL CO LTDULSAN SOUTH KOREA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bang, Sung Hwan Incheon, KR 7 21
Chun, Jeong Hee Incheon, KR 5 13
Jeong, Ji Seon Incheon, KR 7 20
Lee, Sang Youb Incheon, KR 10 113
Park, Kyung Yeol Incheon, KR 3 0
Shin, Ju Hee Incheon, KR 8 21
Son, Jin Ryul Incheon, KR 14 9

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