Anti-human MUC1 antibody Fab fragment

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United States of America

PATENT NO 10517966
SERIAL NO

16462143

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Abstract

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The problem to be solved is to provide an anti-human MUC1 antibody Fab fragment that is expected to be useful in the diagnosis and/or treatment of a cancer, particularly, the diagnosis and/or treatment of breast cancer or bladder cancer, and a diagnosis approach and/or a treatment approach using a conjugate comprising the Fab fragment. The solution is an anti-human MUC1 antibody Fab fragment comprising a heavy chain fragment comprising a heavy chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 8 or 10, and a light chain comprising a light chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 12, and a conjugate comprising the Fab fragment.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INC5-1 NIHONBASHI-HONCHO 2-CHOME CHUO-KU TOKYO 1038411 JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Doihara, Hitoshi Tokyo, JP 9 20
Hirayama, Kazunori Tokyo, JP 12 20
Hosogai, Naomi Tokyo, JP 7 81
Morinaka, Akifumi Tokyo, JP 9 45
Shirai, Hiroki Tokyo, JP 23 170

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