Mixed lineage kinase inhibitors for HIV/AIDS therapies

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10485800
APP PUB NO 20150297587A1
SERIAL NO

14648404

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Abstract

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Disclosed are methods for treating an individual infected with a retrovirus that comprise administering to the individual effective amounts of a mixed lineage kinase inhibitor and antiretroviral drug. In further aspects, disclosed are methods for treating an individual infected with a retrovirus that comprises administering an antiretroviral drug formulated into a crystalline nanoparticle comprising a surfactant, and a MLK inhibitor. Still further disclosed are methods for treating an individual infected with a retrovirus that comprises administering a composition comprising both an antiretroviral and MLK inhibitor formulated into a crystalline nanoparticle, which comprises a surfactant. Still further disclosed are compositions that comprise an antiretroviral drug, a MLK inhibitor, and a surfactant, wherein the composition is a crystalline nanoparticle. Compostions comprising MLK inhibitors with other drugs in nanoparticulate form, and methods of there use, are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF ROCHESTERRIVER CAMPUS 518 HYLAN BUILDING ROCHESTER NEW YORK 14627

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dewhurst, Stephen Rochester, US 27 255
Gelbard, Harris A Pittsford, US 14 68
Gendelman, Howard E Omaha, US 28 57

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