Integrated organ-on-chip systems and applications of the same

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United States of America Patent

PATENT NO 10444223
APP PUB NO 20190064144A1
SERIAL NO

16049025

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Abstract

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A microclinical analyzer usable for analysis of one or more bio-objects, each bio-object including an organ or a group of cells includes a fluidic network having a plurality of fluidic switches, a plurality of fluidic paths in fluid communication with the plurality of fluidic switches, and one or more on-chip pumps coupled to corresponding fluidic paths; a sensor array coupled to the fluidic network; and a microcontroller for individually controlling the plurality of fluidic switches and the one or more on-chip pumps of the fluidic network as so to operably and selectively deliver an effluent of at least one bio-object to the sensor array for detecting properties of the effluent, or to a predetermined outlet destination.

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Patent Owner(s)

Patent OwnerAddress
VANDERBILT UNIVERSITYCENTER FOR TECHNOLOGY TRANSFER AND COMMERCIALIZATION 305 KIRKLAND HALL 2201 WEST END AVENUE NASHVILLE TN 37240

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Block, Frank Emmanuel Nashville, US 2 47
Cliffel, David E Nashville, US 7 140
Markov, Dmitry A Nashville, US 14 116
McCawley, Lisa Joy Nashville, US 3 105
McKenzie, Jennifer Robin Nashville, US 3 105
McLean, John A Nashville, US 10 266
Reiserer, Ronald S Nashville, US 37 269
Samson, Phillip C Nashville, US 3 57
Wikswo, John P Brentwood, US 51 534

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