Use of thermophilic nucleases for degrading nucleic acids
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United States of America Patent
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Aug 20, 2019
Grant Date -
Jun 30, 2016
app pub date -
Mar 13, 2014
filing date -
Mar 15, 2013
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Abstract
The present invention relates to the use of a thermophilic nuclease for degrading nucleic acids in vivo and/or in situ, wherein the thermophilic nuclease is heterologous to the host cell and is produced by the host rather than being added exogenously. The present invention further relates to a genetically modified cell which was produced according to the above method. The present invention is particularly beneficial in inactivating the biological activity of recombinant DNA in biomass or biomass-derived products.
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