Process for the enantiomeric resolution of apremilast intermediates

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United States of America Patent

PATENT NO 10370329
APP PUB NO 20180134660A1
SERIAL NO

15573290

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Abstract

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A process for the resolution of racemic 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine using novel chiral salts is disclosed. An L-phenylalanine p-toluene-sulfonamide salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine and a di-p-toluoyl-L-tartaric acid salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine are also provided.

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Patent Owner(s)

Patent OwnerAddress
MYLAN LABORATORIES LTDHYDERABAD 500033

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Achanta, Nageshwara Rao Hyderabad, IN 1 0
Dandala, Ramesh Hyderabad, IN 34 78
Dorasala, Sivaprasad Maharashtra, IN 1 0
Jayachandra, Sureshbabu Maharashtra, IN 9 0
Kaushik, Vipin Kumar Hyderabad, IN 8 5

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