Method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, a device and cassette for performing this method
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United States of America Patent
Stats
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Jul 9, 2019
Grant Date -
May 3, 2018
app pub date -
May 19, 2016
filing date -
May 20, 2015
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series includes carrying out a first synthesis run including the steps of: a) providing water containing fluorine-18; b) trapping the fluorine-18 from the water provided in step a) on an anion exchange material; c) eluting the trapped fluorine-18 from the anion exchange material to a reaction vessel of first radiopharmaceutical synthesis cassette; d) preparing a radiopharmaceutical incorporating the eluted fluorine-18 using the first radiopharmaceutical synthesis cassette; where steps a)-d) are repeated in at least one subsequent run using another radiopharmaceutical synthesis cassette; and where the method includes a reconditioning step of the anion exchange material between two consecutive runs. A device for performing this method and a cassette for use in the device are also disclosed.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
OUT AND OUT CHEMISTRY S P R L | 6060 GILLY (CHARLEROI) |
International Classification(s)
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- C07D:HETEROCYCLIC COMPOUNDS
- C07C:ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07B:GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS TH....
- B01J:CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, CO....
- C01D:COMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, ....

- 2016 Application Filing Year
- C07H Class
- 1039 Applications Filed
- 891 Patents Issued To-Date
- 85.76 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Tadino, Vincent Luc Antoine | Chastres, BE | 5 | 0 |
# of filed Patents : 5 Total Citations : 0 | |||
Villeret, Guillaume André René | Dimont, FR | 4 | 0 |
# of filed Patents : 4 Total Citations : 0 |
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Patent Citation Ranking
- 0 Citation Count
- C07H Class
- 0 % this patent is cited more than
- 6 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Jan 9, 2027 |
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jan 9, 2031 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text

Legal Events
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Dec 28, 2022 | MAFP | MAINTENANCE FEE PAYMENT | free format text: PAYMENT OF MAINTENANCE FEE, 4TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1551); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY year of fee payment: 4 |
Jul 09, 2019 | P | Publication | |
Jun 19, 2019 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
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May 03, 2018 | P | Published | |
Dec 06, 2017 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:TADINO, VINCENT LUC ANTOINE;VILLERET, GUILLAUME ANDRE RENE;REEL/FRAME:044524/0281 Owner name: OUT AND OUT CHEMISTRY S.P.R.L., BELGIUM Effective Date: Dec 06, 2017 |
Oct 31, 2017 | FEPP | FEE PAYMENT PROCEDURE | free format text: ENTITY STATUS SET TO UNDISCOUNTED (ORIGINAL EVENT CODE: BIG.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
May 19, 2016 | F | Filing | |
May 20, 2015 | PD | Priority Date |

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