Mutant OPAA enzyme with increased catalytic efficiency on organophosphorus compound GP

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United States of America Patent

PATENT NO 10335465
SERIAL NO

15880747

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Abstract

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The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2′-dimethylcyclopentyl methylphosphonofluoridate).

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THE UNITED STATES OF AMERICAAS REPRESENTED BY THE SECRETARY OF THE ARMY WASHINGTON DC 20515

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dixon, Melissa M Abingdon, US 4 7
Guelta, Mark A White Marsh, US 22 83
Harvey, Steven P Lutherville, US 17 49
McMahon, Leslie R Aberdeen, US 3 3

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