Hydrolases, nucleic acids encoding them and methods for making and using them
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 4, 2019
Grant Date -
Mar 3, 2016
app pub date -
Oct 7, 2015
filing date -
Mar 7, 2003
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The invention provides hydrolases, polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides, e.g., enzymes, having a hydrolase activity, e.g., an esterase, acylase, lipase, phospholipase (e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity) or protease activity, including thermostable and thermotolerant hydrolase activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The hydrolase activities of the polypeptides and peptides of the invention include esterase activity, lipase activity (hydrolysis of lipids), acidolysis reactions (to replace an esterified fatty acid with a free fatty acid), transesterification reactions (exchange of fatty acids between triglycerides), ester synthesis, ester interchange reactions, phospholipase activity and protease activity (hydrolysis of peptide bonds). The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts, including the manufacture of cosmetics and nutraceuticals. In another aspect, the polypeptides of the invention are used to synthesize enantiomerically pure chiral products.
First Claim
Family
International Classification(s)
- C12C:BREWING OF BEER
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- A61Q:USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C10M:LUBRICATING COMPOSITIONS
- A23L:FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A23K:FODDER
- D06M:TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D0....
- C11D:DETERGENT COMPOSITIONS
- A23C:DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE; MILK OR....
- C11C:FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FAT....
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully