Enzyme-encapsulated nanoparticle platform
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United States of America Patent
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May 28, 2019
Grant Date -
Aug 25, 2016
app pub date -
Sep 17, 2014
filing date -
Sep 17, 2013
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Abstract
Disclosed are methods, systems, and devices for implementing nanoparticles to encapsulate biomolecules such as enzymes. In one aspect, a nanoparticle device includes a shell structure including an internal layer structured to enclose a hollow interior region and include one or more holes penetrating through the internal layer, and an external layer formed of a porous material around the internal layer; and an enzyme contained within the interior region of the shell structure, the enzyme having entered the shell structure through the one or more holes and incapable of passing through the external layer, in which the pores are of a size that prevents the enzyme to pass through the pores while permitting substances smaller than the pore size to pass through the pores.
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