Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans
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United States of America Patent
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Jan 1, 2019
Grant Date -
Apr 13, 2017
app pub date -
Oct 21, 2016
filing date -
May 7, 2009
priority date (Note) -
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status (Latency Note)
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Abstract
Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- A23L:FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT....
- C07B:GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS TH....
- C08B:POLYSACCHARIDES; DERIVATIVES THEREOF
- C08L:COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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