Pharmaceutical composition for treating cancer including 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol as active ingredient

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United States of America Patent

PATENT NO 10166203
APP PUB NO 20180133168A1
SERIAL NO

15564027

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to an anticancer use of a novel compound, i.e., 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol. The compound of the present disclosure effectively inhibits the growth of cancer cells and tumors in vitro and in a xenograft animal model. The compound of the present disclosure illustrates an anticancer activity by inhibiting a DNA binding activity of transcription factor STAT 3 in cancer cells, inducing apoptosis of cancer cells, and reducing the expression of a cell cycle regulatory protein. The compound of the present disclosure can be developed as an active ingredient of a strong anticancer drug.

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Patent OwnerAddress
CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONCHUNGCHEONGBUK-DO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ham, Young-Wan West Orem, US 1 4
Hong, Jin-Tae Chungcheongbuk-do, KR 6 17
Jung, Heon-Sang Chungcheongbuk-do, KR 1 4
Kim, Chun-Sik Chungcheongbuk-do, KR 8 395
Lee, Hee-Pom Chungcheongbuk-do, KR 1 4

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