Microneedle device having a peptide therapeutic agent and an amino acid and methods of making and using the same

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United States of America Patent

PATENT NO 10154957
APP PUB NO 20170209367A1
SERIAL NO

15480813

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Abstract

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A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.

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Patent Owner(s)

Patent OwnerAddress
KINDEVA DRUG DELIVERY L P11200 HUDSON ROAD WOODBURY MN 55129

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fenn, Percy T St. Paul, US 5 116
Johnson, Peter R Eagan, US 24 596
Zhang, Ying Woodbuy, US 923 12176

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