Screening of conjugated antibodies
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United States of America Patent
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Nov 20, 2018
Grant Date -
Dec 3, 2015
app pub date -
Jul 10, 2013
filing date -
Jul 13, 2012
priority date (Note) -
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Abstract
Provided is a method for the functionalization of immunoglobulins through the use of transglutaminase, including methods for screening functionalized antibodies for characteristics of interest, antibody compositions comprising a plurality of functionalized antibodies, and functionalized antibodies with rodent constant regions.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07F:ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CO....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C07D:HETEROCYCLIC COMPOUNDS
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- C07C:ACYCLIC OR CARBOCYCLIC COMPOUNDS
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- C07K:PEPTIDES
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