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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
EPOCH COMPANY LTD	2-2 2-CHOME KOMAGATA TAITO-KU TOKYO

International Classification(s)

• B26B:HAND-HELD CUTTING TOOLS NOT OTHERWISE PROVIDED FOR....
• A63H:TOYS, e.g. TOPS, DOLLS, HOOPS, BUILDING BLOCKS

• 2017 Application Filing Year
• B26B Class
• 408 Applications Filed
• 277 Patents Issued To-Date
• 67.90 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Sakai, Ryo	Tokyo, JP	102	754
# of filed Patents : 102 Total Citations : 754

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Patent Citation Ranking

• 0 Citation Count
• B26B Class

• 0 % this patent is cited more than
• 7 Age

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date
7.5 Year Payment	$3600.00	$1800.00	$900.00	Apr 2, 2026
11.5 Year Payment	$7400.00	$3700.00	$1850.00	Apr 2, 2030

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
October 02, 2018	US,10086311,B2   US10086311B2	GRANTED PATENT AS SECOND PUBLICATION
February 15, 2018	US,20180043276,A1   US20180043276A1	FIRST PUBLISHED PATENT APPLICATION

Full Text

US Patent Application No: 12240888

Composition comprising aflibercept and a variant thereof, and related methods and uses

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Abstract

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Provided is a composition comprising aflibercept and a variant thereof, wherein the variant is a truncation variant with a truncated VEGF binding portion of aflibercept, and wherein the content of the truncation variant is less than or equal to about 20% by mass percentage. Also provided is a pharmaceutical formulation comprising the composition. Further, provided are a method for detecting the variant and use of the variant in quality inspection or quality control of an aflibercept-containing product.

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Description

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Claims

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