Therapeutic oligonucleotides comprising pyrazolotriazine nucleotide analogues
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Aug 28, 2018
Grant Date -
Jun 18, 2015
app pub date -
May 30, 2013
filing date -
May 31, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Disclosed herein are double-stranded RNA nucleic acid molecules, which include at least one pyrazolotriazine nucleotide analog and have been modified to exhibit one of the following, increased on-target activity, increased target specificity, enhanced nuclease stability, reduced off target activity and/or reduced immunogenicity when compared to an unmodified or similarly modified dsRNA; pharmaceutical compositions comprising such molecules and methods of use thereof in therapy.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully