Peptide combinations and uses thereof in treating dust mite allergy
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United States of America Patent
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Aug 28, 2018
Grant Date -
Sep 1, 2016
app pub date -
Dec 23, 2014
filing date -
Dec 23, 2013
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Abstract
The invention relates to combinations of peptides or variants thereof derived from a portion of an amino sequence of a house dust mite allergen, e.g. the allergens Der p 1, Der f 1, Der p 2 and/or Der f 2. Such peptides comprise at least one T cell epitope and a significant high number of patients in a worldwide population will have HLA alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by a dust mite.
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