Compound and analogues for tracing histone acetylation inhibitors PET imaging for diagnosis and treatment of tumors
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United States of America Patent
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Oct 6, 2016
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Oct 6, 2016
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Abstract
The present invention relates to a group of compounds for nuclear medicine imaging through F-18 labeled histone acetylation inhibitors (HDACi) of indole or indoline benzoyl amine and its derivatives, and provides a series of nuclear medicine imaging agents that bind with HDAC overexpression in vivo for diagnosis of malignant tumors discovered in the nuclear medicine imaging tracing.
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