ISIS PHARMACEUTICALS, INC.

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Patent Activity in the Last 10 Years

Technologies

Intl Class Technology Matters Rank in Class
 
  
 
C07H SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS 1988
 
  
 
A61K PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES 73182
 
  
 
C12Q MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS 6958
 
  
 
C12N MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF 50117
 
  
 
C07D HETEROCYCLIC COMPOUNDS 12150
 
  
 
A01N PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF 986
 
  
 
C12P FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE 891
 
  
 
G01N INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES 5201
 
  
 
C07K PEPTIDES 4132
 
  
 
C07C ACYCLIC OR CARBOCYCLIC COMPOUNDS 3135

Top Patents (by citation)

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Recent Publications

Publication # Title Filing Date Pub Date Intl Class
2004/0023,917 Oligonucleotide compositions and methods for the modulation of the expression of B7 proteinMay 23, 03Feb 05, 04[A61K]

Recent Patents

Patent # Title Filing Date Issue Date Intl Class
9550990 Regulation of epigenetic control of gene expressionDec 12, 05Jan 24, 17[C12N]
9359608 Modulation of signal transducer and activator of transcription 3 (STAT3) expressionJul 23, 14Jun 07, 16[C07H, C12N]
9096636 Chimeric oligomeric compounds and their use in gene modulationNov 04, 03Aug 04, 15[C07H, C12N]
8969316 Compounds and methods for modulating expression of DGAT2Oct 26, 12Mar 03, 15[C07H, A61K, C12Q, C12N]
8933213 Antisense modulation of fibroblast growth factor receptor 4 expressionSep 28, 12Jan 13, 15[C07H, A61K, C12N]
8895529 Antisense modulation of fibroblast growth factor receptor 4 expressionJun 12, 13Nov 25, 14[A61K, C12N]
8859514 Modulation of C-reactive protein expressionOct 11, 10Oct 14, 14[C07H, A61K, C12Q, C12N]
8853178 Antisense modulation of PTP1B expressionJul 06, 11Oct 07, 14[C12N]
8778900 Modulation of eIF4E-BP1 expressionJan 24, 05Jul 15, 14[C07H, C12Q]
8710023 Antisense modulation of C-reactive protein expressionDec 02, 11Apr 29, 14[A61K, C07H, C12Q]

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Expired/Abandoned/Withdrawn Patents

Patent # Title Status Filing Date Issue/Pub Date Intl Class
2016/0017,328 DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATIONAbandonedJul 21, 15Jan 21, 16[C12N]
2015/0184,156 MODULATION OF APOLIPOPROTEIN (a) EXPRESSIONAbandonedMar 12, 15Jul 02, 15[C12N]
2015/0141,636 OLIGOMERIC COMPOUNDS COMPRISING BICYCLIC NUCLEOSIDES AND HAVING REDUCED TOXICITYAbandonedJul 25, 14May 21, 15[C12N]
2015/0126,725 5' AND 2' BIS-SUBSTITUTED NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROMAbandonedOct 03, 14May 07, 15[C07H]
2015/0057,329 COMPOUNDS AND METHODS FOR MODULATING EXPRESSION APOBAbandonedMar 17, 14Feb 26, 15[C12N]
2015/0011,001 COMPOSITIONS AND METHODS FOR OPTIMIZING CLEAVAGE OF RNA BY RNASE HAbandonedJun 13, 14Jan 08, 15[C12N]
2014/0357,856 CHIMERIC OLIGOMERIC COMPOUNDS COMPRISING ALTERNATING REGIONS OF NORTHERN AND SOUTHERN CONFORMATIONAL GEOMETRYAbandonedJun 13, 14Dec 04, 14[C12N]
2014/0275,207 ANTISENSE COMPOUNDS AND METHODS OF USE THEREOFAbandonedMar 14, 13Sep 18, 14[C07H]
2014/0206,750 MODULATION OF APOLIPOPROTEIN (a) EXPRESSIONAbandonedJan 24, 14Jul 24, 14[C12N]
8586554 Compounds and methods for modulating expression of PTP1BExpiredMay 07, 07Nov 19, 13[C12N]
8580948 Modulation of forkhead box O1A expressionExpiredJun 22, 12Nov 12, 13[C07H]
2013/0296,400 ANTIDOTES TO ANTISENSE COMPOUNDSAbandonedMar 04, 13Nov 07, 13[C12N]
2013/0252,243 METHODS OF DETERMINING POTENCY OF CHEMICALLY-SYNTHESIZED OLIGONUCLEOTIDESAbandonedDec 21, 12Sep 26, 13[C12Q]
2013/0237,585 MODULATION OF DYSTROPHIA MYOTONICA-PROTEIN KINASE (DMPK) EXPRESSIONAbandonedJul 19, 11Sep 12, 13[C12N]
8518904 Modulation of STAT 6 expressionExpiredJan 13, 12Aug 27, 13[A61K, C07H, C12N]
2013/0217,749 MODULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE-MITCHONDRIAL (PEPCK-M) EXPRESSIONAbandonedJun 10, 11Aug 22, 13[A61K]
8486904 Antisense modulation of fibroblast growth factor receptor 4 expressionExpiredOct 01, 08Jul 16, 13[A61K, C07H]
2013/0178,513 MODULATION OF EIF4E EXPRESSIONAbandonedFeb 28, 13Jul 11, 13[C07H]
8476421 Modulation of stat5 expressionWithdrawnFeb 22, 10Jul 02, 13[C07H]
2013/0156,845 LIPID FORMULATED SINGLE STRANDED RNAAbandonedApr 29, 11Jun 20, 13[A61K]

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